Hi everyone. I have been on baby aspirin for about 3 weeks now and I posted above that I had what I *thought*
might have been implantation spotting yesterday. Today there is a little spotting also. Its only a few dropsI am feeling quite depressed about it and have failed this cycle. When my nurse told me the baby aspirin could cause internal bleeding can it also cause spotting also? Sorry I know its a stupid question to ask ↑
Tracy72: I noticed after my first and second m\c I would get some spotting around o and between, very very light. I didn't start taking the baby aspirin until this cycle, and I had the same spotting in the first cycle post m\c so I would guess not related. The internal bleeding with aspirin nomally refers to gastrointestinal bleeding (stomach and intestine) The research says that the risks are increased from 1.4% if you aren't taking anything to 2.5% if you are. And signs of gastrointestinal bleeding are blood in stool or vomit. Oh and it's totally not a stupid question, with all the stuff they ask us to do and they don't really explain what the side effects mean and with what's happened it's just natural to worry. But I wouldn't count yourself as completely out for the cycle just yet. :) Are you going to test, you might be far enough along, those Walmart tests have worked for me at 12 days.... ↑
Oh and Deniseb: I have another forum I'm on (they have a triploidy loss section) where a girl had 5 m\cs, two were trisomy, and she had a little boy in September. I don't think she posts much anymore but just to give you some hope. babycenter.com/boards/bcuspreg (no dashes) oh and I would think that since the FSH test is such a simple one and it would help rule out egg quality as an issue, since there is still theory that some of the chromosomal issues can be related to egg quality. Trisomy happens a lot more in older women, so I would think it would be worth ruling out as an issue. Then onto the chromosomal tests.... FYI. The girl that I mentioned had normal chromosome tests. ↑
Sorry I don't post very often, but things are crazy in my life right now. Just thought I would give an update.
Tomorrow is my appt with the hematologist, after which I will have an appt on 12/12 with one of the High Risk/Perinatologists in my clinic. We'll see if I end up doing Lovenox/Heparin injections or not.
In other news, I was waiting for my 1st period after induction of labor of our 16 week daughter we lost, and joined Curves to try to lose some of these extra pounds and was having a lot of abnormal bleeding and cramping after each workout. I mentioned it to one of the docs here, who ordered an U/S and it was found that I (after 7 weeks) had retained products of conception. I had to have a D&C procedure 2 weeks ago as a result, so now I'm dealing with my cycles being abnormal all over again.
I'm really starting to feel very frustrated and sad that so much time has passed. My son just turned 7 on 11/19 and the older he gets, the more I worry about our family having that "yours/mine" feeling. I want my children to be able to be close to one another, as I have a brother from my mom's second marriage who is 16 years younger than me, and he has never really felt like a brother to me--more like a nephew or something. I am so thankful to have my son, but really want a baby with my husband. : ( ↑
I wanted to update my crazy story....my bloodwork from two weeks ago confirmed that I did not ovulate, so I didn't start the lovenox...the other day I took a hpt which was positive...so frantically went in that day for bloodwork which came back negative. Not pregnant wtih a positive home test..I am not on any fert. drugs either. I have never heard of this. I guess I am one of the .10% that isn't acurate. I am still late, but assuming that its just a fluke. I am looking forward to starting to ttc in January. After the last mc in August, I never thought I would be ready by now. It is still hard to see my friends who are all having their babies that were due at the same time as mine. I appreciate you all for being there and writing on here every day. ↑
kellidp..I didn't think I would be ready so soon to ttc again. My m/c was in March. I started injectable fertility drugs in October. This is 2nd cycle and praying. My luteal progesterone (think that's what they called it) on day 21 was 27.7!!! That's higher than it ever was in the beginning of any pregnancy I've ever had. So, I'm trying not to get my hopes up since it doesn't mean that anything happened! Your mind starts playing tricks on ya though. I'm on cd 22, very bloated (which could be from the drugs I read) and just afraid to hope too much. I thought I would never be ready to try again. But my desire to have another baby has beaten out my fears (today anyway!!). I think treating the MTHFR and PAI-1 before and during p/g just might do the trick. My son is 3 and he keeps asking me "mommy, do you want another baby?". At first I thought I wante d to get pg again to fill that hole in my heart that losing my twins left. But I know it's much deeper than that. ↑
Hey guys-i sure hope someone out there is reading this before tonight-----------hey quick Q for any of you IVF-ers: does the ganirelix shot go on the inner part of your thigh? gosh, i hope so, cuz that's where i'm putting it tonight! i have a bunch of teeny weeny eggs on my right side. (the left is apparently playing this month out again) so say some prayers that these guys do some fast maturing or else there's 3 thousand bucks of drugs alone down the drain. btw, why didn't anyone tell me how absolutely miserable this was going to be on me? this is by far, the most stress i've had since all this started. the money, the emotional, the what if it doesn't work, the 'i-look-like a heroin-addict' marks all over my body, and oh yeah, all my friggin friends who are getting pg at the drop of a hat! i had to get a massage today for some much needed attitude adjustment. not sure if it helped. sincerely, desperately in need of some prayers, liz. ↑
Liz-----------I'm sorry but I never did the ganirelix shot. If it is a subcutaneous injection then the leg/thigh is correct. Was the needle about an inch or less? I'm happy to hear that you some have eggs developing. They seem to mature pretty fast (at least in my case they did). I assume that is the norm. ------I know exactly how you are feeling. Between meds and procedure we spent around $8000 out of pocket. I was sooo sure it would work. I was devastated when it didn't. However, the very next month I conceived naturally. I was honestly in shock! My OB says that it is quite common to conceive shotly after using fertility drugs. She doesn't know why but it happens frequently. I guess what I am saying is 'if' for some reason it doesn't work, don't give up! I didn't even know I ovulated the month I got pg. My heart and my prayers are with you!!!!!!! ↑
Hi my name is Amanda i am 21 yrs old and just got diagnosted w/ mthfr after having a still born baby boy at 33 weeks.I have two copies of the a1298c mutation one from my dad And one from my mom.At the same time that I was diagnosed with the mthfr i got the results back from the placenta testing that they did and they found clotting in the placenta.The Dr. told me they did not know if the clotting was from the mthfr or due to the fact that the baby had been pasted away inside me for 48 hours before i knew. Me and my husband want to have a baby very badly. I was wondering if anyone knew if it is harder to conceive if you have this mutation? Because I had not been on birth control and we did not get pregnant for 3 yrs (not that we were relly trying all that time we were just trying to let nature take its course). I am also on the folic acid in addition to prenatles and baby asprine do you think i should get a vitamine b-12 supplement as well? ↑
Hey ladies & Nate-
first of all, I'm thinking of you and your wife, nate, you have my prayers and best wishes! what a beautiful christmas gift! secondly, stac, thanks for the quick response. you're always right there when i need you! :o) the shot was fine, yes, about 1 1/2 long, however, the little bugger stung. we're going ahead with ivf this week - thursday and sunday. keep your fingers crossed, and your prayers loud! i'm soooo nervous...hopefully my acu gal will help out with any stress. and thirdly, amanda, welcome. i am terribly sorry for your loss. how very hard for you. as you will read from days (months actually) back, the Bvites are very helpful as well. they don't hurt, so if nothing else, they'll at least make you feel as though you're doing everything you can. in fact, my doc told me to take the FA 4mg, but on my own, i started taking the low dose aspirin and the b's (of course with her consent) because of the overwhelming amount of evidence i've seen and heard. so good luck to you. take care everyone. lw ↑
Good luck Liz! We'll be thinking of you this week.**********Welcome Amanda! I have the same mutation you do - homozygous for A1298C. If your doctor didn't recommend that you see a hematologist I would highly recommend it, and take the placenta results with you. Did they run blood tests on your baby as well for clotting? The hematologist will probably ask that your dh be tested as well so that you can assess risks for children. More of a concern than the A1298C would be C677T. If your dh carries that than it would put your children at risk for the heterozygous combination that's most dangerous. As for the type that you and I have, my understanding after combing through many studies is that it has not been tied to clotting problems that C677T has. The research has not been as thorough, but I couldn't find a single study linking the homozygous A1298C condition to any problems. In fact, being homozygous for A1298C actually makes you much less likely to get certain types of cancer. Don't get me wrong, it still freaks me out, but if you ever see anything reference "mthfr" as a risk you will often find that it is either homozygous C677T or compound heterozygous C677T/A1298C that was the problem - and homoz. A1298C was not. Please, anyone, pass on any info you have that shows otherwise. Find out what your homocysteine levels are - that is typically what hematologists will look for and most do not treat unless your mutation is having an effect on homocysteine levels. A1298C has not been shown to affect those levels. Now, as for treatment, my doctor did recommend 4mg of FA. I take B12 & B6 on my own in fairly low doses, prenatal elite (has an easily digested form of FA), and baby aspirin (recommended by RE). Baby aspirin/heparin I had heard was NOT recommended unless you have a history of clotting problems or if your homocysteine levels are normal. I am quitting the BA today because I started my AF and it is SO MUCH HEAVIER than normal (no i wasn't pg). Good luck! ↑
Hi girls- haven't posted for a while. Still read almost every day though. Does anyone know when to count day 1 on your cycle? I spot for about a week, and then bleed very heavily for a couple of days, and then kind of spotting again. Is the first day when you see any bleeding or the heavy bleeding? My cycles used to be so normal, and since the miscarriages I have this spotting now. Just wondering if any of you know. Good luck to all of you doing the fert.drugs and IVF. I can't imagine the stress- I really feel for you. My prayers are with all of you. Keep the faith- Trish ↑
TriciaFaye, I spot for 2-3 days then start, so my doctor has me start day one on the first day of "normal" bleeding. I have a question on Foltab. How many mcg of folic acid does it contain? I was under the impression that it had 2.5, but now I'm thinking it may only have 800mcg. I can't find the link on this forum that compares all the drugs. Tracey ↑
TriciaFaye: I've heard the same thing as Tracey, first day of "normal" bleeding, spotting doesn't count. Tracey: Looks like Foltab is 800 mcg xubex.com/medications.shtml But here is a list of all the 2.5 mg ones. I'm taking Folgard right now, very easy pill to take, which is nice. fvleiden.org/ask/77.html Though they do have one with Calcium FolgardOS that I was going to ask my doc about since I know I don't get enough calcium. Hope that helps... ↑
Hello everyone---- Well, it has finally hit. I am starting to get anxious/nervous. I am now 15 4/7 weeks along. I have weekly ultrasounds that have all been normal so far but all of a sudden I am starting to worry. I have been sooo optimistic but I think it is just that I am in my 'danger zone'. Deep down I believe that I am going to make it through this pregnancy but very nervous now that something crazy is going to happen. I' m not sure if my dreams are affecting my thoughts or my subconscious is affecting my dreams but I had my first 'bad' dream of this pregnancy last night and I was rushed into the ER at 20/21 weeks because I started funneling. I know it is just a dream but reality hit pretty quick.----------Just needed to vent a little....thanks ↑
Stacy- I am 27 weeks and had a very similar reaction at about 15 weeks. After 9-10 weeks I got very optimistic and as I approached 17 weeks (the time I previously lost my 1st baby) I started freaking out. Disgusting, scary and intense dreams. I didn't want to go to the doctor because I convinced something was wrong. Everything has been great, however. I go in for ultrasounds every 6 weeks and see the doctor inbetween those visits. About 3 days before either I start to get nervous and the dreams come back. So far so good but the nervousness and anxiety never completely leave. I just hope I can make it and continue to be as optimistic as I can. Talking to my mother really helps. My husband feels similar to me and we sometimes just worry each other. Keep your head up. Every week is an accomplishment:-) ↑
hi guys- not such good news. in fact, i've been crying pretty much all day. i had my egg aspiration today. we had 5 eggs, but 4 'degenerated' meaning they withered away into oblivion. so that left us with ONE good egg. a transfer is pending, determining on the development of this one good egg. i was so sure this would be a sure thing. i guess stac was right, nothing is for sure. however, the more scary thing for me is that the doctor said she doesn't know if these bad eggs were a fluke, or that's the reason behind my conception problems. perhaps they've all been 'bad eggs' all these months. in fact, that's prob why i had the chemical pg in feb. she said there's nothing they can do to fix that problem except to just ...hope for a good egg in the mix. so, assuming this egg doesn't divide well, or doesn't implant, our next stupid f--- plan is to switch drugs and do some heavy overloading of shots (perhaps 2ce a day) to get a really large amount of eggs. yeah, right....like i have the money or emotional strength to do this again. i feel like i have just entered the world of 'you can't have anymore children'. i'm only 32 for pete's sake! oh man, my confidence is spiralling into nonexistence. anyhow, best wishes to the rest of you. lw ↑
Nope...no transfer. The fertilized egg was 'severly abnormal'. It's all becoming clear to me now...I've already got an appt with an adoption attorney. Any advice on that route would be surely helpful...I forget who it was that already has a child through adoption who i think is now pg...lemme know. lw (ps. still gonna try IVF one more time but for me it's just really for the sake of closure. I am expecting nothing positive to come of it. I need to know for sure that we're done and let my grieving begin.) ↑
Liz- I am so sorry about your news. I am one that adopted a baby girl almost 2 years ago--she is an absolute gift from God, in the exact same way that my biological son is. We were at the hospital when she was born, and we were able to take her home with us at 48 hours. She was born in FL, and we live in SD. We keep in close contact with her birth mother, whom seems more like a family member. I have never felt like I wasn't her mom- 100%. I feel terrible that you are going through this hard time, but I also know there is a miracle waiting for you. If you need any help or info. on adoption, please let me know. It is the best thing we have ever done. My prayers are with you. Tricia Tracey and aalice--thank you for your response- that's great help. aalice- I think the Folgard that I'm on has 2.25 or 2.5mg of FA, but I take an extra 2.5 mg to be safe. My friend who lost her baby at 20 wks wasn't on any, and then she got pg again and was on 5mg of FA, and delivered a healthy girl. Good luck! Tricia ↑
Liz, I am so sorry about the IVF. That really sucks--there is no other way to say it. We may be in the same boat with the eggs. I just turned 36 and had the E2 tests done (FSH compared with Estradiol on Day 2) and they found that it is off. This means my eggs are most likely not great. My dr says to act quickly (which you are way ahead of me) using drugs, but we are fighting a battle against time. We do have a back up plan--my sister has offered her good eggs for an IVF. (I seem to be the genetic garbage can for my family.) If that doesnt' work, we will adopt, and then as fate would have it, I would then get pregnant with triplets w/o trying!!! Anyway, keep you chin up--I have found that predicting our chances of having a baby is much like predicting the weather--no one really knows. Tracey ↑
I have a question and would like your input. As you have read my story 4 mc's etc. etc. all with chromosonal abnormalities I went to see a genetic counselor last week. I asked her about MTHFR and should I get tested, she explained that if all Caucasians were tested for this it will show about 50% or more do have the mutation she said it is part of our genetic race more than black or asian races. Have you heard this? ↑
Deniseb: It's kinda convoluted, but what I've found from the reading is that it's about the same amount of occurence in caucasian and asian (most research done in japan), but not as much in blacks. But the 50% number she is giving you is a high estimate for people that are heterozygous for one variant, which there is much debate right now, but many say it is not an issue to carry one variant. The concern is if you are homozygous (for the C677t one, more so than the A1298C one) or if you are compound heterozygous for one of each. There is also debate on if you have either of those two diagnosis whether you should have to do blood thinners (heparin\lovenes) throughout pregnancy, most think that if your homocysteine levels are low enough you don't have to, but there are others that disagree. My doc was rather resistant on doing the clotting tests also. Her arguement was that many people have it and are fine, and if you find out you do have it, then you have to treat it. I didn't quite buy into that so she let me do the tests, she's great that way, and if taking a vitamin and a baby aspirin can make a difference, I'd rather know... Also just for my overall health, regardless of the whole baby process... LIZ: Many hugs to you. I think the whole not knowing and hoping and crashing cycle is one of the worst parts of this crazy journey. TRICIA: Yeah they managed to get me in for a perinat consult today so I'll ask then if I should be one a double dose. The Folgard pills are just so much easier and they are small and easy to take and they don't taste bad... ↑
Hi girls-and Nate,
Its been a few weeks since I've been near a computer(I have to use the library's). Liz-I'm sorry to hear your news. I know its been rough for you.
Nate and Want1more--you guys are seriously close to delivery now!!
I am now 17wks. and although I am convincing myself not to worry, our last 2 losses were at 18 and 20 wks. I have faith that God will take care of us.
I have felt the baby move for the last week. So exciting! I go on the 27th for the lon u/s and hopefully we will see if its a "Mason Garrett" or a "(insert girl's name here)" We have no girls name.
My OB raised my Heparin to .75cc 2x a day now. I feel very optimistic and cautiously excited.
You are all in my thoughts. Merry Christmas and Happy Holiday!! ↑
The ups and downs of this genetic defect are overwhelming. I will agree that overall I feel much better taking the additional vitamins. I am currently 28 weeks pregnant and counting. Went for another ultrasound on Tuesday and everything looked great. They did the 4D ultrasound (don't quite understand it) but go the best baby pictures possible so far. One is waiting for a frame. I go back in 6 weeks for another ultrasound and I am continuing to to take folgard and baby aspirin. Any doctor who says you are better off not knowing has no empathy for what others have to go through. In my family we are beginning to connect to problem to past and current problems besides me. I feel like in some strange way I have helped out. Anyway-- as long as my little girl stays active I'm happy:-) Good luck to all who are pregnant or ttc. There is a miracle out there for everyone. Waiting is the hardest part. ↑
Hi All. I hope you don't mind mebutting in on this thread. I've been recently diagnosed with compound Hetero mthfr and am currently 22 weeks. I've been taking aspirin all along because my RE suggested it as I've had 4 losses. I also have had 3 normal pregnancies. I've been to my RE, my Peri and my ob and have come back with the same answers from each of them. No heparin therapy is necessary. My homocysteine levels are low at 2 and that's their reasoning. I had to beg my ob for Folgard. I've had many ultrasounds with this baby and the last at 20 weeks and she was measuring right on - no signs of any ntds. I don't honestly know if I need the heparin therapy. This mthfr is so ambiugous and it seems like everyone is on a different therapy. As a last ditch effort to get some answers and finally a 4th opinion I am seeing a hematologist on Thursday. What do you all think? Aspirin and Folgard enough with normal homocysteine levels? Thanks if you got this far. :-) ↑
